A REVIEW OF PENTOBARBITAL SODIUM USE

Observe Intently (1)pentobarbital will minimize the level or effect of fentanyl intranasal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Closely. Coadministration of fentanyl with CYP3A4 inducers could lead on to a minimize in fentanyl plasma concentrations, insufficient efficacy or, perhaps, advancement